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Cosmetics, Make-up and Fashion  

Welcome to this presentation of high class cosmetic products. Please click at the banners or product links to learn more or buy.

Further down on this page there is also an article about skin and body rejuvination.

Quality cometics of all famous producents

More examples: Galenic, Monteil Z,. Bigatti, Gatineau, Murad, 4711, Gabriele Strehle, Miss Sixty, Academie, Gale Hayman, Molyneux, Adrien Arpel, Gale Hayman Beverly Hills, Mont Blanc,, Adrienne, Vittadini, Geoffrey, Beene Montana, Agent, Provocateur, Gianfranco Ferre, Morgan, Aigne r, Gilles Cantuel, Moschino, Alain Delon, Giorgio Armani, Naomi Campbell, Alexander McQueen, Giorgio, Beverly Hills, Narciso Rodriguez, Alfred Sung, Gloria Vanderbilt, Nautica, Alyssa Ashley, Gres, Nike, Animale Gucci, Niki De Saint, Phalle, Annick, Goutal, Guepard Nikos Anucci, Guy Laroche, Nioxin Aramis, Halston, Norell, Aubusson, Hanae Mori, Origins.
 

Please scroll down to see some cosmetic product examples form the house Borghese:

Caring and healing cosmetic products

For men and women. Makeup that also gives protection and treatment against skin damage. Also corrective make-up that covers skin defects.  Skin care, day care, night care, foundation beige - fairy light - light - fair - medium - tan - dark, cleanser, body care,  lipsticks, lip gloss, lip liner, shadow, blush, flower water treatment, loose setting powder, remover, eye make up, face make-up, nail color and treatment, hair care, shampoo, hair cleansing, treatment for dry or fat hair, perfume for men and women, eau de cologne, eau de toilette, after shave, cover cream, leg and body cover cream, smooth indulgence foundation, skin caring foundation, concealing treatment make-up, corrective leg and body make-up.

Examples of make-up brands: Bare Escentials, Dermablend, City Cosmetics, Exuviance.

Emblex Day Cream

Protecting and rejuvinating day cream to use alone or under make-up. Emblex incorporates all the advantages of modern cosmetic science, but formulated only with pure, natural ingredients. Gentle to the skin, Emblex eases away the stress and inflammation that cause premature wrinkling and discoloration. Never heavy or greasy.  Emblex absorbs immediately, with gentle, wrinkle smoothing action that continues for up to 16 hours after application. The benefits to the skin are cumulative, so that your skin improves steadily by regular use. Rebuilds your skin to be soft, smooth, and supple again. By clicking at this banner, you will find this and other products for regenerating skin treatment.
 

Create your own T-shirts, underwear, sportswear and other clothes - SpreadShirt designer - By clicking at the banners here, you get into a page with tools you can use to decide how your clothes shall look. Then you can order the clothes with your chosen background colors, pictures, ornaments, tecture, accessories and texts. You have hundreds of pictures to choose from and you can make your own texts. You can make clothes with your personal design for children, teenage girls and boys and adult men and women.

If you live in America, please click at this banner.

If your home is in UK, please click here.

Some other skin care and health items

Murad Exfoliating Acne Treatment Gel 3.4 oz FREE Shipping. 115% Price Protection. Deep clean pores while controlling breakouts with this powerful clarifier Clear away while clearing up. This patented formula blends retinol with salicylic and glycolic acids to penetrate pores and sweep them super-clean. Hydrogen peroxide purifies without drying to keep skin clear and healthy. U.S. Patents 6,071,541/5,972,999 Additional features and benefits: • Retinol and glycolic acid eliminate excess skin cell buildup to control breakouts • An anti-inflammatory blend of licorice, chamomile and aloe vera helps to reduce redness and irritation • 90% proven effective when used in combination with Acne Complex® products (Clinically proven in over 90% of users to reduce blemishes in just 4 weeks) Usage Every day after cleansing and toning, massage a thin layer over face and neck. For optimal results, follow with Skin Perfecting Lotion and recommended Murad sunblock during the day.

Topical medicines to treat many specific skin conditions - If you need some product to treat specific skin problems, or cosmetics that also contain ingredients to help against skin diseases, you will find what you need by clicking to the banners below: Here are items from several produsents to treat ailments like: Acne, rashes, sun-damage, cellulites, thin skin, edema, rosacea, miscolored skin, and much more.

More anti-aging and skincare products: Items to reduce skin aging and general aging. Products to cure skin problems.

More health products: Disease prevention, cures for diseases, sexual health.

Some skincare and health information

Here is an article about rejuvination therapy or efforts to achieve rejuvination.. To see a list of all skincare articles, please go here. To see a list of general health information, please go here.

A SURVEY ABOUT APPROACHES TO ANTI-AGING AND REJUVINATION

Rejuvination is taking away aging symptoms and restoring the property of a jouthful body. Anti-aging is a more wide term. It encompasses both the prevention of aging symptoms and remending an aged body to restore juvenile properties.

What is aging

Aing is a combination of several types of damages to the body:

One key part is the reduction of the structures at the end of chromosomes, the so called telomere chains. This reduction occur every time a cell divide. However, these structure is built up again by processes using the enzyme telomerase. This restoration is however not completely effective in all cells, and therefore the telomere chains tend to shorten to a point where the cell cannot divide any more.

Another key part is genetic dammage by free radicals and oxidative processes. In the skin ultraviolet light also damage the genome. The body has enzymatic repair processes also for this type of damage, but they are not entirely effective. The body also has processes to kill cells that are too much damaged to be repaired, or has gone so far to be cancer cells. But damaged cells that should be killed do not always get eliminated.

A third key component is damage of structure proteins between the cells, for example the proteine collagen. Again free radicals play a key role to effect this damage. In the skin also utraviolet light and environmental impact effect the damage. Also here, the body has repair processes where the immune system play a key role, but again the repair is not entirely effective.

The forth component is the loss of cells, because of damage that is so hard that cell dies, All cells in the body divide to replace lost cells. Some cells also or only is replaced by dividing of more primitive stem cells. Also nerve cells divide or are replaced by division of stem cells, even though this long was thought not to occur. But agiain, the replacement process is not entirely effective.

A fifth component is aggregation of vaste between the cellc in the body. The immune system can tidy away such vaste, but do not manage to do it alltogether.

As seen, the body has processes to eliminate all the components of the aging process and repair the damage done, but people age because this repair process is not effective enough.

Also the proteins and the genes for proteins taking place in the repair process is damaged by several types of impact, for example by free radicals, oxidative processes and in the skin by ultraviolet light. The repair processes that are very effective when a person is young, but tend to be less so as one ages, because the repair mechanisms themselves are hurt by several types of impact.

Rejouvination in myth and tradition

For a long time it was believed that magic could restore the youths of an individual. A common belief was also that there existed some natural objects with the power of restoring youth, either by having magical properties or by having some special natural properties.

Some of the myths tell about the Spring of jouth or Fountain of Youth, with the property that people bathing in the spring or in water from it will get young again.

Other objects believed to be able to restore youths was pearls or stones hidden somewhere, or special plants growing in some secret places.

These ancient myths are not without any reality. There exist really plants or natural objects that have shown to help againts certain aging symptoms, for example Ginseng and the arctic plant Rodiola Rocea. The assumption that there may be even more powerfull plants growing at some hidden places is therefore quite logical.

The myths about these jouth restoring objects made people go on long expeditions to find these, or people having power sent out expeditions to look for them.

These expeditions continued well into the 16th century, or perhaps continues to this day, but nowadays in a more scientific fashion. A famous Spanish explorer Juan Ponce de León led the expedition around the Caribbean islands and into Florida to find the Fountain of Youth. Led by the rumours, the expedition continued the search and many perished. The Fountain was nowhere to be found as locals were unaware of its exact location.

Most religions believe in a life after death, either for all people or as a revard for having lived a good life. If such a life shall be good, a rejuvination must also take part when the person is resurrected. Therefore most religions believe in the possibility of ethernal youth after death.

Since the emergence of philosophy, sages and self-proclaimed wizards always made enormous efforts to find the secret of youth, both for themselves and for their noble patrons and sponsors. It was widely believed that some potions may restore the youth.

Another commonly cited approach was attempting to transfer the essence of youth from young people to old. Some examples of this approach were sleeping with virgins or children (sometimes literally sleeping, not necessarily having sex), bathing in or drinking their blood.

The quest for rejuvenation reached its height with Alchemy. All around the Europe and also beyond alchemists were looking for the Philosopher's Stone, the mythical substance that, as it was believed, could not only turn lead into gold, but also prolong life and restore youth. Although the set goal was not achieved, Alchemy paved the way to the scientific method and so to the medical advances of today.

A myth is not necessarily only untruthful. There may be something right in some of the myths, even though they are propagated in a form not useful for practical purposes.  The alchemists may have found something that later on has been lost or dismissed as bare superstition, or has been suppressed by those having power, and did not want ordinary people to gain the power of prolonging life and quality of life.

 

Modern developments

According to modern science, there are no natural laws preventing successful rejuvenation. Aging is an accumulation of damage to macromolecules, cells, tissues and organs. If any of that damage can be repaired, the result is rejuvenation.

There have been many experiments which have been shown to increase the maximum life span of laboratory animals, thereby achieving life extension. A few experimental methods such as replacing hormones to youthful levels have had considerable success in partially rejuvenating laboratory animals and humans.

There are at least eight important hormones that decline with age: 1. human growth hormone (HGH); 2. the sexual hormones: testosterone or estrogen/progesterone; 3. erithropoietin EPO; 4. insulin; 5. DHEA; 6. melatonin; 7. thyroid; 8. pregnenolone. In theory, if all or some of these hormones are replaced, the body will respond to them as it did when it was younger, thus repairing and restoring many body functions. This seems to be borne out in hundreds of thousands of persons who have replaced hormones for many years, especially human growth hormone (HGH, a.k.a. GH).

Most attempts at genetic repair have traditionally involved the use of a retrovirus to insert a new gene into a random position on a chromosome. But by attaching zinc fingers (which determine where transcription factors bind) to endonucleases (which break DNA strands) homologous recombination can be induced to correct and replace defective (or undesired) DNA sequences. The first applications of this technology are to isolate stem cells from the bone marrow of patients having blood disease mutations, to correct those mutations in laboratory dishes using zinc finger endonucleases and to transplant the stem cells back into the patients.

Regenerative medicine using three different strategies:

Implantation of stem cells from culture into an existing tissue structure
Implantation of stem cells into a tissue scaffold that guides restoration or
Induction of residual cells of a tissue structure to regenerate the necessary body part.
A salamander can not only regenerate a limb, but can regenerate the lens or retina of an eye and can regenerate an intestine. For regeneration the salamander tissues form a blastema by de-differentiation of mesenchymal cells, and the blastema functions as a self-organizing system to regenerate the limb [2].

Yet another option involves cosmetic changes to the individual to create the appearance of youth. These are generally superficial and do little to make the person healthier or live longer, but the real improvement in a person's appearance may elevate their mood and have positive side effects normally correlated with happiness. Cosmetic surgery is a large industry offering treatments such as removal of wrinkles ("face lift"), removal of extra fat (liposuction) and reshaping or augmentation of various body parts (abdomen, breasts, face).

There are also, as always in history, many fake rejuvenation products that do not work. Chief among these are powders and sprays and gels and homeopathic that claim to be "growth hormone". Authentic growth hormone can only be injected, because the 191 amino-acid protein is too large to be absorbed through the mucous membranes, and would break up in the stomach if it is swallowed.

 

Strategies for Engineered Negligible Senescence (SENS)

A leading researcher of gerontology, Dr aubry de Grey has proposed a strategy combination for the reversal of aging and cell degeneration that he calls SENS( Strategies for Engineered Negligible Senescence)

- Cell loss can be repaired (reversed) just by suitable exercise in the case of muscle. For other tissues it needs various growth factors to stimulate cell division, or in some cases it needs stem cells.
- Senescent cells, can be removed by activating the immune system against them. Or they can be destroyed by gene therapy to introduce "suicide genes" that only kill senescent cells.
- Protein cross-linking can largely be reversed by drugs that break the links. But to break some of the cross-links we may need to develop enzymatic methods.
- Extracellular garbage (like amyloid) can be eliminated by vaccination that gets immune cells to "eat" the garbage.
- For intracellular junk we need to introduce new enzymes, possibly enzymes from soil bacteria, that can degrade the junk (lipofuscin) that our own natural enzymes cannot degrade.
- For mitochondrial mutations the plan is not to repair them but to prevent harm from the mutations by putting suitably modified copies of the mitochondrial genes into the cell nucleus by gene therapy. The mitochondrial DNA experiences a high degree of mutagenic damage because most free radicals are generated in the mitochondria. A copy of the mitochondrial DNA located in the nucleus will be better protected from free radicals, and there will be better DNA repair when damage occurs. All mitochondrial proteins would then be imported into the mitochondria.
- For cancer (the most lethal consequence of mutations) the strategy is to use gene therapy to delete the genes for telomerase and to eliminate telomerase-independent mechanisms of turning normal cells into "immortal" cancer cells. To compensate for the loss of telomerase in stem cells we would introduce new stem cells every decade or so.
Dr. de Grey has created the Methuselah Mouse Prize, which awards money to researchers who can rejuvenate mice.

The last strategy of deleting the genome for telomerase is directly silly. Reduction of the telomerase chains at the end of chromosomes by cell division is a main cause of aging. Telomerase works to repair destroyed teleomerase chains and thus counteracts aging. A high telomerase activity is not the only change by cancer and cells with high telomerase activity are not necessarily cancer cells. Hightening the telomerase activity can actually be an imprtant and necessary strategy to be able to eliminate ageing.

Aubrey de Grey's claim that the only significant effect of nuclear DNA (nDNA) damage is cancer is open to dispute, and this impacts both of his last two strategies (neither of which is appropriately described as "repair"). Evidence of significantly reduced oxidative damage to mitochondrial DNA (mtDNA) and negligible oxidative damage to nDNA in calorie restricted rats is misleading because DNA repair capability declines with age. Thymine dimer removal (a form of DNA repair) is about five times greater in newborn fibroblasts than in fibroblasts from the elderly. So although DNA damage other than mutation (cancer), may be small in the young, it increases greatly with age. Moving mtDNA into the nucleus would not be as beneficial as he presumes if nDNA is subject to such a decline in DNA repair with age.

A comparison of the heart mitochondria in rats (4-year lifespan) and pigeons (35-year lifespan) showed that pigeon mitochondria leak fewer free radicals than rat mitochondria, despite the fact that both animals have similar metabolic rate and cardiac output. Pigeon heart mitochondria (oxidative phosphorylation protein Complexes I & III) showed a 4.6% free radicals leak compared to a 16% free radical leak in rat heart mitochondria [5]. Rather than copy mtDNA into the nucleus, it may be a more effective strategy to reduce free radical production in mitochondria by making human Complex I more like the Complex I found in birds, by copying from the bird genome. A comparison of 7 non-primate mammals (mouse, hamster, rat, guinea-pig, rabbit, pig and cow) showed that the rate of mitochondrial superoxide and hydrogen peroxide production in heart and kidney were inversely correlated with maximum life span . A similar study of 8 non-primate mammals showed a direct correlation between maximum lifespan and oxidative damage to mtDNA in heart & brain. There was a 4-fold difference in levels of oxidative damage and a 13-fold difference in longevity, supportive of the idea that mtDNA oxidative damage is not the only cause of aging.

The segmental progerias ("accelerated aging" diseases) are part of the evidence that the weakest link in extending lifespan is DNA repair -- along with the fact that DNA repair capability correlates with maximum lifespan in mammals . There is much that could be done to improve DNA repair both in the nucleus and in the mitochondria. We could study organisms like the bacterium Deinococcus radiodurans [9] and adapt their enzymes to our cells. Thus, improved DNA repair and reduced free radical production (by Complex I proteins taken from birds) may be much more cost effective strategies than SENS for reducing aging-damage, extending maximum lifespan and preventing cancer.

(Most of this informationis fetched from wikipedia.org and is therefore fre for reuse.)

 

COSMETIC PRODUCT EXAMPLES: Here are some examples of the products from the house Borghese. By clicking at any link you get to a store with all products from this house and from a lot of other houses.

Borghese Spa Bronzer Travel Set: Tanning Face Crm+ Tanning B/Crm+ Splendore M/U+ B/Glow+ Bronzer Trio+ Brush Spa Bronzer Travel Set: 1x SPA Solare Self Tanning Face Cream SPF15 28g 1x SPA Solare Self Tanning Body Cream SPF15 70g 1x Splendore Brightening MakeUp 30ml 1x Splendore Brightening Body Glow 30ml 1x Spa Bronzer Trio - #Powder Multi Bronzer 3.4g 1x Brush

Borghese Sali Esfoliante Salt Scrub ( Travel Size Unboxed ) Sali Esfoliante Salt Scrub ( Travel Size Unboxed )

Borghese Hydro Mineral Creme Finish Make Up - No. 11 Espresso A light crème makeup for a flawless natural-looking complexion Provides light to medium coverage & a luminous finish Helps eliminate imperfections & non-pore clogging Formulated of exclusive Acqua di Vita “Living Water” complex Maintains long wearing & keeps skin comfortable all day Ideal for normal-dry & dry-very dry skin types

Borghese Perfetta Lip Pencil - No. 14 Amalfi Red ( Unboxed ) Helps prevent lipstick from fading feathering & bleeding Hydrates & soothes skin a unique Living Water Complex Gives full color long lasting & soft blending Accurately defines the lines on lip color Dermatologist tested

Borghese Hydro Mineral Dual Effetto Powder Makeup SPF8 - No. 06 Cappucino A versatile long wearing powder for makeup or touch-ups throughout the day Apply wet for fuller finish while dry for sheer finish Provides soft & even application & protection from sun damage Formulated of exclusive Acqua di Vita “Living Water” complex Soothes skin & restores to its natural moisture balance Fragrance free. Suitable for all skin types

Borghese Active Mud Face & Body Gently detoxifying toning and polishing the skin Hydrates and firms the skin Apply generously to clean skin Avoid lip & eye area Leave on for 2 to 5 minutes Rinse off thoroughly with warm water using sponge or washcloth

Borghese Mini Nail Lacquer Mixed Pack # 1 ( Unboxed ) Mini Nail Lacquer Mixed Pack # 1 ( Unboxed ): 1x Mini Nail Lacquer - #01 Passione 4.7ml 1x Mini Nail Lacquer - #02 Oro Verde 4.7ml 1x Mini Nail Lacquer - #03 Primo Blu 4.7ml 1x Mini Nail Lacquer - #32 Opera Red 4.7ml 1x Mini Nail Lacquer - # Bronzeo 4.7ml

Borghese Cleansing Cream Purifiant Deeply cleanser Leaves skin fresh Hydrates skin Use morning and evening Massage into lather over wet face and throat Rinse thoroughly with warm water

Borghese Cura Naturale Time Defying Cream Makeup SPF8 - #04 Cammeo ( Dry to Very Dry Skin ) Fortified with unique restorative Acqua di Vita mineral water complex Protects skin from free-radical damage with anti oxidant vitamins Conditions & replenishes skin with a hydrating ceramide Minimizes fine lines with advanced micro-milled pigments Adjustable coverage from sheer to medium to full Leaves a smooth velvety finish & a perfect complexion Perfect for dry to very dry skin

Borghese La Moda Matte Lipcolour - No. 03 Misto Currant Gives matte moist finish Long wearing & stay-fresh color Not easily dry feather or fade Lightweight & glides on skin smoothly Preserves suppleness of your lips

Borghese Advanced Spa Lift For Eyes A lightweight moisture eye care Diminishes appearance of fine lines and wrinkles Use daily to ease dark circles and puffiness Maintains a brighter fresher & more youthful-looking skin Use morning & evening Suitable for all skin types

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. This information is nutritional in nature and should not be construed as medical advice. This notice is required by the Federal Food, Drug and Cosmetic Act.